Review on Lumpy Skin Disease Virus Characteristics and its Diagnosis in Cattle

Lumpy skin disease is characterized by its signs including eruptive, infectious and occasionally causing death to affected animals. It caused the family Poxviridea genus Capripox with a strain of Neethling virus, double stranded DNA virus. LSD clinical are mainly observed on as nodules (0.5 5 cm in diameter) throughout surface or subcutaneous tissue involving superficial lymph nodes. Diagnosis CaPV based upon laboratory confirmation virus isolation, polymerase chain reaction (PCR) electron microscopy. Field diagnosis often characteristic disease. However, mild subclinical forms require rapid reliable testing confirm diagnosis. Isolation can be made from collected biopsy at post-mortem nodules, lung lesions nodes within first week occurrence signs, before development neutralizing antibodies. There different methods detect antibody blood samples. These serum neutralization test (SNT), indirect fluorescent (IFAT) enzyme-linked immune-sorbent assay. member CaPVs, it has single serotype, do not cause persistent infection, have limited host range vaccines available that may provide long term immunity. attributes increase prospect successfully implementing regional control programs, leading elimination conceivably global eradication.